An Interesting C-Ring Contraction in Paclitaxel (Taxol)

DOI: 10.1016/0040-4039(95)01954-G

Source and publish data:

Tetrahedron Letters p. 8933 - 8936 (1995)

Update date:2022-08-04

Topics:

Authors:

Chen, Shu-Hui

Huang, Stella

Roth, Gregory P.

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Article abstract of DOI:10.1016/0040-4039(95)01954-G

An interesting pinacol rearrangement involving 7-epi-6α-tosylate/triflate-paclitaxel derivatives (6) and (10), with the formation of five-membered C-ring containing analogs (7) and (11), is described.

Full text of DOI:10.1016/0040-4039(95)01954-G

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