Synthesis and antitumor activity of duocarmycin derivatives

DOI: 10.1248/cpb.43.1530

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1530 - 1535 (1995)

Update date:2022-08-03

Topics:

Authors:

Nagamura

Kanda Kanda

Kobayashi

Gomi Gomi

Saito Saito

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.43.1530

A series of duocarmycin B2 derivatives, modified at the phenolic hydroxyl group to ester, carbonate and carbamate, was synthesized. Antitumor activity of these analogs was preliminarily evaluated by assays of growth inhibition of HeLa S3 cells (in vitro)

Full text of DOI:10.1248/cpb.43.1530

NII-Electronic Library Service

Products guided by the article

Product name:8-O-(dimethylcarbamoyl)DUMB2

Cas No:171599-25-0

R&D Labs maybe for 171599-25-0

C-LAB Chemievermittlung GmbH

Contact:+49-9398-993127

Address:Untertorstr. 27
BIOS CHEMICALS

Contact:+33-5-34012600

Address:28 ZA des Pignès
SICHUAN ZHONGBANG NEW MATERIAL CO., LTD

website:http://www.zhongbangst.com

Contact:86-830-2585019

Address:sichuan,china
Jiangxi Lanqi Fine Chemical S&T Co., Ltd.

Contact:+86-21-64891143

Address:XinJiShan Industrial Area, Zhangshu City, JiangXi Province, China
Borun Chemical Co.,Ltd.

Contact:+86-574- 87178138; 87297407

Address:No. 809, Liudingxingzuo, cangsong road, Ningbo, China

Relevant to this article

Vinyliden-Uebergangsmetallkomplexe XXXVIII. Alkin-, Alkinyl-, Vinyliden-, Allenyliden- und Benzyl-Rhodiumkomplexe mit dem Phosphinoether iPr2PCH2CH2OMe als ein- und zweizaehnigen Liganden

Doi:10.1016/0022-328X(95)05784-M
(1995)
(±)-4-amino-4,5-dideoxyribose, (±)-4-amino-4-deoxyerythrose, and (±)-dihydroxyproline derivatives from N-dienyl-γ-lactams

Doi:10.1002/hlca.19950780510
(1995)
An Asymmetric Nitroolefination of α-Alkyl-γ-and δ-Lactones with Modified Nitroenamines

Doi:10.1016/0040-4020(95)00683-Y
(1995)
A Novel Synthesis of (R)- and (S)-α-Alkylated Aspartic and Glutamic Acids: α-Alkylated Aspartic Succinimides as New Type of β-Turn Type II and II' Mimetics

Doi:10.1016/0040-4020(95)00665-U
(1995)
2-Aza-1,3-Dienes: Methods of Synthesis and Stereochemical Studies

Doi:10.1016/0040-4020(95)00657-T
(1995)
A convenient method for the preparation of N-aryl and N-alkyl-O-methyl hydroxylamines

Doi:10.1080/00397919508015485
(1995)

Article Doi