Novel and Efficient Synthesis of 1β-Methylcarbapenems Utilizing Cyclization of Hypervalent Iodonium Ylides

DOI: 10.1016/0040-4039(95)01703-K

Source and publish data:

Tetrahedron Letters p. 8043 - 8046 (1995)

Update date:2022-07-29

Topics:

Authors:

Kume, Masaharu

Kubota, Tadatoshi

Iso, Yasuyoshi

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Article abstract of DOI:10.1016/0040-4039(95)01703-K

1β-Methylcarbapenems were efficiently synthesized utilizing acid- and rhodium(II)-catalyzed cyclization of iodonium ylide intermediates, which were easily prepared from the corresponding β-keto ester derivatives.

Full text of DOI:10.1016/0040-4039(95)01703-K

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