
Chemical and Pharmaceutical Bulletin p. 1598 - 1600 (1995)
Update date:2022-08-03
Topics:
Kobayashi
Wang
Ohyabu
Kurosu
Kitagawa
An efficient asymmetric synthesis of a cyclic depsipeptide arenastatin A (1) is described. 1, isolated from the marine sponge Dysidea arenaria, exhibited extremely potent cytotoxicity with IC50 of 5 pg/ml for KB cells, and in this context the s
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