Diastereoselective synthesis of merucathin: The singlet oxygen ene reaction (Schenck reaction) as a key step towards an E-configured β-amino allylic alcohol

Article abstract of DOI:10.1055/s-1995-4071

An enantio- and diastereoselective synthesis of the naturally occurring merucathin is reported. The singlet oxygen ene reaction of the bis-Boc-protected allylic amine 3, which was prepared from L-alanine, was employed as key step for this regio- and diast