Journal of Medicinal Chemistry p. 3294 - 3302 (1994)
Update date:2022-09-26
Bisset, Graham M. F.
Bavetsias, Vassilios
Thornton, Timothy J.
Pawelczak, Krzysztof
Calvert, A. Hilary
et al.
Sixteen γ-linked dipeptide and four L-Glu-γ-amide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583) have beensynthesized and evaluated as inhibitors of thymidylate synthase (TS).Z-blocked L-Glu-γ-L-linked dipepti
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