European Journal of Medicinal Chemistry p. 769 - 778 (1995)
Update date:2022-08-03
Topics:
Yebga, A.
Menager, S.
Verite, P.
Farnoux, C. Combet
Lafont, O.
In order to study the competition between hepatic hydroxylation and desulfuration in the thiobarbiturate series, two compounds bearing a branched side chain with a tertiary carbon atom in position ω-1 were administered to rats over about one week.Urine and faeces were collected and extracted.The metabolites isolated were identified.It was shown that desulfuration was not the major metabolic pathway, and that, when it took place, it remained a minor process and was accompanied by γ-hydroxylation into a tertiary alcohol. thiobarbiturate series / metabolism / oxidation / desulfuration
View MoreTaizhou Green Peptide Trading Co., Ltd.
Contact:--15314709780
Address:Room 1501, No71, Yuehe Road, Taizhou City, Zhejiang Province, China
website:http://www.herbpurify.com
Contact:0086-028-85249238
Address:Room709-C1,Incubator Building, Tianfu Life Science Park No.88,Keyuan Road,Gaoxin district,Chengdu City,Sichuan Prov,China
Contact:+86-571-87010026
Address:202, Zhenhua Road,
website:http://www.hope-chem.com
Contact:86-21-58090396-805
Address:Floor 4, Building 5, No.588 Tianxiong Road, Zhoupu International Medical Zone, ShangHai, China
Contact:86-21 60347964
Address:No.1304, West Meilong Road, Minhang District, Shanghai, China
Doi:10.1016/0008-6215(95)00199-4
(1995)Doi:10.1246/bcsj.40.2950
(1967)Doi:10.1134/S1070428014020237
(2014)Doi:10.1016/S0040-4039(00)73257-6
(1994)Doi:10.1016/S0040-4039(00)76974-7
(1994)Doi:10.1071/CH15065
(2015)
