Asymmetric Bridging Annulation Reaction Involving the Intramolecular Conjugate Addition of Chiral Imines to Enoates: Access to a Polycyclic System Related to the Taxane Core

Article abstract of DOI:10.1016/0957-4166(95)00347-R

(R)-1-phenylethylamine-induced cyclization of ketoenoate 24 led to a 2:1 mixture of "all-cis" polycyclic adducts 25 and 26, structurally related to the taxane series.