Directing effect of functional groups in ruthenium-catalyzed addition of substituted acetophenones to an olefin

Article abstract of DOI:10.1016/0022-328X(95)05607-Q

Ruthenium-catalyzed addition of 3'-methyl-, 3'-trifluoromethyl-, and 3'-N,N-dimethylaminoacetophenones to an olefin proceeds site selectively at 6' C-H bonds to give the 1:1 C-H/olefin addition products in high yields.In contrast, the addition of 3'-metho