Tetrahedron Letters p. 3391 - 3394 (1999)
Update date:2022-08-03
Topics:
Brossette, Thierry
Valleix, Alain
Goujon, Laure
Creminon, Christophe
Grassi, Jacques
Mioskowski, Charles
Lebeau, Luc
An enzymatically stable analogue of AZT-triphosphate is prepared in 7 steps starting from thymidine. The thymine moiety is functionalized at N3 to allow the further cross-linking to a carrier protein for subsequent immunization of rabbits in order to raise specific antibodies directed against AZT-TP.
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