An Efficient Asymmetric Functionalization to Highly Substituted Pyrrolidines

Article abstract of DOI:10.1016/0957-4166(95)00353-Q

A stereoselective route to enantiomerically and diastereomerically pure pentasubstituted pyrrolidines has been developed by using reductive deoxygenation of quaternary α-hydroxy N-Boc pyrrolidine derivatives prepared from alkylation of the functionalized