Tetrahedron Letters p. 9515 - 9518 (1995)
Update date:2022-08-03
Topics:
Scio, Kohji
Wada, Takeshi
Sakamoto, Kensaku
Yokoyama, Shigeyuki
Sekine, Mitsuo
A novel cyclouridylic acid 1 having a propylene bridge between the uracil 5 position and the 5′-phosphate group was synthesized. The structure of 1 was analyzed by 1H NMR, and CD spectroscopy, which suggested that the cyclonucleotide 1 was highly stabilized in a considerably rigid g′/C3′-endo conformation with the base orientation of and. The molecular mechanics calculation of 1 gave a similar conclusion.
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Doi:10.1071/CH9952023
(1995)Doi:10.1016/0040-4039(95)02160-4
(1996)Doi:10.1016/S0020-1693(00)87916-5
(1987)Doi:10.1021/ol049675n
(2004)Doi:10.1246/cl.1984.409
(1984)Doi:10.1021/jm00195a004
(1979)
