6-Amino-1,11-dimethyl-6,7-dihydro-5H-dibenzo[a,c]cycloheptene-6-carbox ylic acid: The first chiral α-amino acid without asymmetric carbon atom

Article abstract of DOI:10.1016/0957-4166(95)00440-8

The title compound 4, possessing a biaryl axis as the sole source of chirality, has been prepared in the enantiomerically pure (R) as well as racemic form by two alternative procedures starting from dibromide 1.