Synthesis and estrogen receptor binding affinities of the major human metabolites of raloxifene (LY139481)

DOI: 10.1016/S0960-894X(97)00142-X

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 993 - 996 (1997)

Update date:2022-08-05

Topics:

Authors:

Dodge, Jeffrey A.

Lugar, Charles W.

Cho, Stephen

Osborne, John J.

Phillips, David L.

Glasebrook, Andrew L.

Frolik, Charles A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00142-X

Glucuronide conjugates 1 and 2, the major metabolites of raloxifene, have been prepared and their molecular interactions with the estrogen receptor determined.

Full text of DOI:10.1016/S0960-894X(97)00142-X

Products guided by the article

Product name:Methyl-1-(4’-tert-butyldimethylsylyl-6-hydroxyraloxifene)-2,3,4-tri-O-acetyl--D-glycopyranuronate

Cas No:174264-49-4

R&D Labs maybe for 174264-49-4

Compro Shijiazhuang Fine Chemical Co., Ltd

Contact:0086-311-89689838

Address:Economic and Technological Development Zone of Shijiazhuang,Hebei
XZL BIO-TECHNOLOGY CO., LTD.

Contact:0086 533 2282832

Address:Zibo，Shandong
WENZHOU M&C FOREIGN TRADE CO.,LTD.

Contact:+86-577-88862917

Address:No.8 Liming West Road,Wenzhou,zhejiang,China
Chongqing Shuangfeng Chemical Co.,Ltd

Contact:+86-23-49850156

Address:No.663,xuanhua Rd,yongchuan,chongqing,China
Changzhou Sunsheng Chem Co., Ltd

Contact:+1-(989)-854-0648

Address:No. 28 Yinshan Rd., Xixiashu Industrial Park

Relevant to this article

Synthesis of heterocyclic ketene aminals with a β-hydroxyethyl group on the nitrogen atom

Doi:10.1080/00397919608003637
(1996)
Synthesis, functionalization and photo-Bergman chemistry of enediyne bioconjugates

Doi:10.1016/j.bmc.2009.07.059
(2009)
PdCl₂-promoted electrophilic annulation of 2-alkynylphenol derivatives with disulfides or diselenides in the presence of iodine

Doi:10.1021/jo9016309
(2009)
Catalyst-free aldol condensation of ketones and isatins under mild reaction conditions in DMF with molecular sieves 4 A as additive

Doi:10.1039/b906684e
(2009)
Palladium-catalysed Hydrosulfination: Synthesis of Sulfonic Acids and S-Alkyl Alkanethiosulfonates from Alkenes, Sulfur Dioxide and Hydrogen

Doi:10.1039/c39930001592
(1993)
A New and Efficient Strategy for Non-stabilized Azomethine Ylide via Photoinduced Electron Transfer (PET) Initiated Sequential Double Desilylation

Doi:10.1039/c39920001313
(1992)

Article Doi