Synthesis and estrogen receptor binding affinities of the major human metabolites of raloxifene (LY139481)

DOI: 10.1016/S0960-894X(97)00142-X

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 993 - 996 (1997)

Update date:2022-08-05

Topics:

Authors:

Dodge, Jeffrey A.

Lugar, Charles W.

Cho, Stephen

Osborne, John J.

Phillips, David L.

Glasebrook, Andrew L.

Frolik, Charles A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00142-X

Glucuronide conjugates 1 and 2, the major metabolites of raloxifene, have been prepared and their molecular interactions with the estrogen receptor determined.

Full text of DOI:10.1016/S0960-894X(97)00142-X

Products guided by the article

Product name:Methyl-1-(4’-tert-butyldimethylsylyl-6-hydroxyraloxifene)-2,3,4-tri-O-acetyl--D-glycopyranuronate

Cas No:174264-49-4

R&D Labs maybe for 174264-49-4

Landz International Company Ltd.

Contact:0086-21-58891610

Address:985 Dongfang Road, Pudong, Shanghai 200122 China
BrightGene Bio-Medical Technology Co., Ltd.

website:https://en.bright-gene.com/

Contact:+86-512-62551801

Address:Building C25 - C31, No. 218 Xinghu Road, Suzhou Industrial Park, Suzhou, Jiangsu, China.
Taixing Joxin Bio-tec Co.,Ltd.

website:http://www.joxbio.com

Contact:86-523-87558858 87612088

Address:No.88, chengdong industrial park
Guangxi Bonger Pharmaceutical Co., Ltd

website:http://napo.lookchem.com/

Contact:+86-18817331185

Address:Donghai Industrial Zone, Tiandong Country,Guangxi,China
HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Contact:+86-186-02659358

Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China

Relevant to this article

Synthesis of heterocyclic ketene aminals with a β-hydroxyethyl group on the nitrogen atom

Doi:10.1080/00397919608003637
(1996)
Synthesis, functionalization and photo-Bergman chemistry of enediyne bioconjugates

Doi:10.1016/j.bmc.2009.07.059
(2009)
PdCl₂-promoted electrophilic annulation of 2-alkynylphenol derivatives with disulfides or diselenides in the presence of iodine

Doi:10.1021/jo9016309
(2009)
Catalyst-free aldol condensation of ketones and isatins under mild reaction conditions in DMF with molecular sieves 4 A as additive

Doi:10.1039/b906684e
(2009)
Palladium-catalysed Hydrosulfination: Synthesis of Sulfonic Acids and S-Alkyl Alkanethiosulfonates from Alkenes, Sulfur Dioxide and Hydrogen

Doi:10.1039/c39930001592
(1993)
A New and Efficient Strategy for Non-stabilized Azomethine Ylide via Photoinduced Electron Transfer (PET) Initiated Sequential Double Desilylation

Doi:10.1039/c39920001313
(1992)

Article Doi