Chemical and Pharmaceutical Bulletin p. 1084 - 1089 (1998)
Update date:2022-07-31
Topics:
Ikeda, Masazumi
Hirose, Ken-Ichi
El Bialy, Serry A. A.
Sato, Tatsunori
Yakura, Takayuki
Bayomi, Said M. M.
1-[2-(o-Iodophenyl)acetyl]-2-(prop-2-enyl)-2-vinylpyrrolidine (17), upon treatment with palladium(II) acetate [Pd(OAc)2] in the presence of tripheoylphosphine and triethylamine in refluxing acetonitrile, gave the monocylization product 20 as the major product along with a small amount of the tandem cyclization product 21. On the other hand, treatment of the 1-[2- (o-iodophenyl)aeetyl]-1-azaspiro[4.4]non-8-en-7-one (25) with Pd(OAc)2, 1,3- bis-(diphenylphosphino)propane, tributylphosphine, and silver carbonate in boiling N,N-dimethylformamide afforded the cyclized product 27 in 51% yield.
View MoreContact:+86-371-86058576
Address:NO.32, Jingsan Road, Zhengzhou, China
Shaanxi Sinuote Biotech Co.,Ltd
Contact:+86-29-68859685
Address:No 18,Taiyuan Road ,Xi'an city ,China
Chengdu CSH Pharmaceutical Co.,ltd
Contact:+86-(28)-85321971
Address:Block B,New Hope Int. Tian Fu New District, Chengdu, Sichuan, China
Hangzhou Mole's Science & Technology Co.,Ltd.(expird)
Contact:+86-571-56880228
Address:15F Guodu development Building, NO.182 Zhaohui Road
Shanghai Hongbang Medical Technology CO.,. Ltd
Contact:13671516988 /18917636693
Address:Room1, No67 Building, Yongde Road369, Wujing Town, Minhang Districy, Shanghai CIty, China.
Doi:10.1039/c7nj03999a
(2018)Doi:10.1080/1065657X.2002.10702089
(1942)Doi:10.1007/BF00908995
(1967)Doi:10.1016/0040-4039(96)00092-5
(1996)Doi:10.1016/0040-4039(96)00144-X
(1996)Doi:10.1055/s-1996-4197
(1996)
