Nucleosides and Nucleotides p. 349 - 359 (1996)
Update date:2022-07-29
Topics:
Alvarez, Rosa
San-Felix, Ana
De Clercq, Erik
Balzarini, Jan
Camarasa, Maria Jose
Novel TSAO-T analogues, in which the ribofuranosyl moiety has been replaced by an hexofuranosyl sugar moeity, have been prepared and evaluated for their inhibitory effect on HIV-1 replication in cell culture. In contrast to the prototype compound TSAO-T, the hexofuranosyl derivatives proved not active at subtoxic concentrations.
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