Synthesis of (±)-2-methyl-(2'-hydroxy-4'-methylphenyl)-2-hepten-4-one (Turmeronol B)

Article abstract of DOI:10.1016/0040-4039(96)00241-9

The first total synthesis of the racemic compound is described. 2-Hydroxy-4-methylacetophenone was used as starting material and transformed into the target molecule in 6 steps. The synthetic Turmeronol B displays spectral properties identical to those reported for the natural compound leading to the confirmation of the proposed structure.