Bioorganic and Medicinal Chemistry Letters p. 679 - 682 (1996)
Update date:2022-08-03
Topics:
Gilmore, John L.
Hays, Sheryl J.
Caprathe, Bradley W.
Lee, Chitase
Emmerling, Mark R.
Michael, Walter
Jaen, Juan C.
A series of 2-aryl-4H-3,1-benzoxazin-4-ones have been synthesized and tested for inhibitory activity against C1r serine protease. Compounds were found that were equipotent and more selective than the reference compound FUT-175.
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Doi:10.1248/cpb.44.646
(1996)Doi:10.1016/S0968-0896(96)00253-2
(1997)Doi:10.1016/0020-1693(95)04806-5
(1996)Doi:10.1515/znb-1996-0319
(1996)Doi:10.1039/cc9960000877
(1996)Doi:10.1002/poc.3679
(2017)