Stereoselective synthesis of a pyridoxamine coenzyme-amino acid chimera: Assembly of a polypeptide incorporating the pyridoxamine moiety

DOI: 10.1016/0040-4039(96)00207-9

Source and publish data:

Tetrahedron Letters p. 2129 - 2132 (1996)

Update date:2022-08-04

Topics:

Authors:

Sinha Roy, Ranabir

Imperiali, Barbara

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Article abstract of DOI:10.1016/0040-4039(96)00207-9

The stereoselective synthesis of (S)-2-amino-N(α)-(fluorenylmethoxycarbonyl)-3-(α⁴,3-O-bis-tert-buto xycarbonylpyridoxamin-5-yl)propanoic acid (4) was accomplished from pyridoxamine dihydrochloride. A key step is the stereoselective alkylation

Full text of DOI:10.1016/0040-4039(96)00207-9

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