Improved large-scale preparation of 4-iodopicolinic acid

Article abstract of DOI:10.1080/00397919608003557

Dimethylformamide showed a dramatic catalytic effect in the chlorination of picolinic acid with thionyl chloride. Methyl 4-chloropicolinate was directly transformed to 4-iodopicolinic acid in a good yield.

Full text of DOI:10.1080/00397919608003557

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Improved Large-Scale
Preparation of 4-Iodopicolinic
Acid
Olivier Lohse a
a SANDOZ PHARMA AG, Chemical Process Research
and Development Department , CH-4002, Basel,
Switzerland
Published online: 21 Aug 2006.
To cite this article: Olivier Lohse (1996) Improved Large-Scale Preparation of
4-Iodopicolinic Acid, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 26:10, 2017-2025, DOI:
10.1080/00397919608003557
To link to this article: http://dx.doi.org/10.1080/00397919608003557
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