Enantioselective reaction of (}-1-hydroxy-5-methyl-3-vinylcyclohex-2-ene and its acyl derivatives using lipid-lipase aggregates in organic solvent

DOI: 10.1248/cpb.44.665

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 665 - 669 (1996)

Update date:2022-08-03

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Authors:

Shimizu Shimizu

Akita Akita

Kawamata

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Article abstract of DOI:10.1248/cpb.44.665

The enzymatic esterification or hydrolysis of 1-hydroxy-((±)-1), 1- acetoxy-((±)-2) and 1-butyryloxy-5-methyl-3-vinylcyclohex-2-ene ((±)-3) was carried out using lipid-lipase aggregates. The esterification of (±)-1 provided (1S,5S)-1 with >99% ee using li

Full text of DOI:10.1248/cpb.44.665

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