Tetrahedron Letters p. 2739 - 2742 (1996)
Update date:2022-08-03
Topics:
Wang
Middleton
Thymidine was converted to its 5'(S)-epoxy derivative, which reacted with nucleophiles to give 5'(S)-C-aminomethyl-, 5'(S)-C-azidomethyl, 5'(S)-C-cyanomethyl-, and 5'(S)-C-methoxymethyl-thymidine with defined stereochemistry. 5'-C-Allyl- and 5'-C-nitromethylthymidines were prepared from an aldehyde derivative. Stereochemistry of 5'-C-branched thymidines was assigned with the help of NOE experiments. Four 5'-C-branched thymidines were incorporated into oligodeoxynucleotides.
View MoreHangzhou J&H Chemical Co., Ltd.
website:http://www.jhechem.com/
Contact:+86-571-87396432
Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China
Shanghai doly chemical Co.,Ltd
Contact:+86-21-34716221
Address:No.328,WuHe Roard,MinHang,ShangHai China
Jinan Decheng Hemu Medical Technology Co.,Ltd.
Contact:+86-531-68650525
Address:NO.554 Zhengfeng Road High-new Technology Development Zone
Zhejiang Tianyu Pharmaceutical Co., Ltd.
Contact:+86-576-84177669, 89189665,89189688,84168770
Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
Wuhan Shangrisyn chemicals Technology Co.,Ltd(expird)
Contact:+86-027-84466317 __ +86-15387123698
Address:wuhan - china
Doi:10.1002/anie.199608861
(1996)Doi:10.1016/S0960-894X(97)00216-3
(1997)Doi:10.1007/BF02219402
(1994)Doi:10.1071/CH9960305
(1996)Doi:10.1016/0020-1693(95)04837-5
(1996)Doi:10.1021/ja01608a005
(1955)