Australian Journal of Chemistry p. 189 - 196 (1996)
Update date:2022-07-29
Topics:
Brimble, Margaret A.
Horner, Gillian M.
Stevenson, Ralph J.
The synthesis of aromatic spiroacetal ring systems related to the papulacandins is reported. ortho-Metalation of diisopropylbenzamide, followed by reaction with the electrophiles δ-valerolactone. γ-butyrolactone and γ-valerolactone, provided the keto alcohol adducts (10), (16) and (21) respectively. Reduction of the ketone followed by treatment with acid afforded phthalides (12), (18) and (23). Finally oxidative cyclization with iodobenzene diacetate provided the spiroacetals (7), (14) and (19).
View Morewebsite:https://www.sinoshiny.com/products
Contact:+86-20-62802632;62802633
Address:Room 330 GIGCAS Building,No.511 Kehua Street,Tianhe District
Contact:852-27701081
Address:Room 2509, New Tech Plaza, 34 Tai Yau St., San Po Kong, HK
Nanjing Chemical Material Corp.(NCMC)
website:http://www.njchemm.com
Contact:0086-25-83172879
Address:B12 Technology and Innovation Building, Nanjing Tech University, No.5 New Model Road
Hubei ShiNan Pharmaceutical Chemical co., Ltd.(expird)
Contact:+86-13554447107
Address:Wuhan HongShanOu wu no road 378 future residence building 1 unit 14 layer no. 1401 A
Shandong Xiangde Biotechnology Co., Ltd
Contact:+86 -15066639877
Address:Sanba street
Doi:10.1016/0040-4039(96)00637-5
(1996)Doi:10.3109/00498259509061869
(1995)Doi:10.1002/hlca.19960790305
(1996)Doi:10.1021/ja00481a037
(1978)Doi:10.1055/s-1996-4300
(1996)Doi:10.1021/jm960537g
(1996)
