Total synthesis of (ent)-korupensamine D

Article abstract of DOI:10.1016/0040-4039(96)00524-2

The first total synthesis of the enantiomer of the natural product, korupensamine D (16R), is described. The key steps include a highly efficient preparation of the enantiomerically pure primary amine 4 via the ring opening of aziridine 2 with an arylcupr