Tetrahedron Letters p. 3227 - 3230 (1996)
Update date:2022-08-03
Topics:
Polushin, Nikolai N.
Smirnov, Igor P.
Verentchikov, Anatoli N.
Coull, James M.
The phosphotriester method of oligonucleotide synthesis is shown to be useful for assembly of oligomers containing multiple internal 2'-azido substituents. Subsequent reduction of the azido group(s) with trialkylphosphines provides 2'-amino substituted oligonucleotides.
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(1996)
