
Tetrahedron p. 7727 - 7736 (1996)
Update date:2022-08-05
Topics:
Rodriguez, Ricardo
Estiarte, M. Angels
Diez, Anna
Rubiralta, Mario
Colell, Anna
Garcia-Ruiz, Carmen
Fernandez-Checa, Jose C.
(αR, 3RS, 5S)-3-Amino-N-(2-hydroxy-1-phenylethyl)-5-methylthio-2- piperidones 1 have been synthesized from enamide 2 by subsequent free radical addition of methanothiol on position 5 and amination of 3-position.
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