Synthesis, reactivity and X-ray molecular structure of the activated ester complex [( η5-C5H4COONS) Co( CO) 2] (NS = N-succinimidyl)

Article abstract of DOI:10.1016/0022-328X(95)06058-5

The title compound [(η⁵-C₅H₄COONS)Co(CO)₂] (2) was prepared in high yield (91%) by treatment of the organometallic carboxylic acid [(η⁵-C₅H₄COOH)Co(CO)₂] (1) with N-hydroxysuccinimide in the presence of dicyclohexylcarbodiimide. The activated ester complex 2 was identified by spectroscopic methods, in addition its X-ray structure was determined. Compound 2 crystallizes in the triclinic space group P1 with a = 6.1880(8), b = 9.722(1), c= 10.869(1) A, α = 83.37(1), β = 83.91(1) and γ = 86.30(1)°, V-645(1) A³ and Z = 2. The stability of the above species 2 and its reactivity as labelling agent for amines and amino-esters are investigated and discussed.