Aryl H-phosphonates. Part IV. A new method for internucleotide bond formation based on transesterification of aryl nucleoside H-phosphonate diesters

DOI: 10.1016/0040-4039(96)00846-5

Source and publish data:

Tetrahedron Letters p. 4561 - 4564 (1996)

Update date:2022-08-04

Topics:

Authors:

Cieslak, Jacek

Sobkowski, Michal

Kraszewski, Adam

Stawinski, Jacek

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Article abstract of DOI:10.1016/0040-4039(96)00846-5

Under mild reaction conditions nucleoside aryl H-phosphonate diesters undergo fast and efficient transesterification with suitably protected nucleosides, affording dinucleoside (3'-5') H-phosphonate diesters.

Full text of DOI:10.1016/0040-4039(96)00846-5

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