Antioxidant and cholesterol lowering properties of 2,6-di-t-butyl-4- [(dimethylphenylsilyl)methyloxy]phenol and derivatives: A new class of anti- atherogenic compounds

Article abstract of DOI:10.1016/S0960-894X(96)00273-9

Di-t-butylphenol derivatives were synthesized and evaluated as antioxidants and cholesterol lowering agents. When evaluated in cholesterol- fed rabbits, the compounds were found to exhibit both properties. Of special interest was the finding that several of the compounds elevated HDL cholesterol levels.