Structure-activity relationships of a series of novel (piperazinylbutyl)thiazolidinone antipsychotic agents related to 3-[4-[4-(6- fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2,5,5-trimethyl-4- thiazolidinone maleate

DOI: 10.1021/jm960268u

Source and publish data:

Journal of Medicinal Chemistry p. 4044 - 4057 (1996)

Update date:2022-08-02

Topics:

Authors:

Hrib, Nicholas J.

Jurcak, John G.

Bregna, Deborah E.

Burgher, Kendra L.

Hartman, Harold B.

Kafka, Sharon

Kerman, Lisa L.

Kongsamut, Sam

Roehr, Joachim E.

Szewczak, Mark R.

Woods-Kettelberger, Ann T.

Corbett, Roy

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Article abstract of DOI:10.1021/jm960268u

HP-236 (3-[4-[4-(6-Fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]- 2,5,5-trimethyl-4-thiazolidinone maleate; P-9236) (54) displayed a pharmacological profile indicative of potential atypical antipsychotic activity. A series of piperazinyl butyl thiazolidi

Full text of DOI:10.1021/jm960268u

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