β-Peptides: Synthesis by Arndt-Eistert homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy. and by X-ray crystallography. Helical secondary structure of a β-hexapeptide in solution and its stability towards p

Article abstract of DOI:10.1002/hlca.19960790402

The β-hexapeptide (H-β-HVal-β-HAla-β-HLeu)₂-OH (2) was prepared from the component L-β-amino acids by conventional peptide synthesis, including fragment coupling. A cyclo-β-tri- and a cyclo-β-hexapeptide were also prepared. The β-amino acids we