Synthesis and tryptic hydrolysis of p-guanidinophenyl esters derived from amino acids and peptides

DOI: 10.1248/cpb.44.1577

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1577 - 1579 (1996)

Update date:2022-08-03

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Authors:

Sekizaki, Haruo

Itoh, Kunihiko

Toyota, Eiko

Tanizawa, Kazutaka

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Article abstract of DOI:10.1248/cpb.44.1577

A facile synthetic method for p-guanidinophenyl esters derived from a variety of amino acids and peptides, including D-amino acids, is presented. The kinetic behavior of trypsin towards these synthetic esters, inverse substrates, was analyzed. The spatial

Full text of DOI:10.1248/cpb.44.1577

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