Tetrahedron Letters p. 5487 - 5490 (1996)
Update date:2022-08-02
Topics:
Maguire, Robert J.
Mulzer, Johann
Bats, Jan W.
A series of allyl bromides 3a-c bearing a stereogenic carbon substituent at C-2 are synthesized in four steps from methyl acrylate. These are found to react with aldehydes, mediated by chromium(II) chloride, to furnish syn-4-alkoxyalkan-1-ols 4 in good to
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Doi:10.1021/jo01064a015
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(1996)
