Ugi reactions with trifunctional α-amino acids, aldehydes, isocyanides and alcohols

Article abstract of DOI:10.1016/0040-4020(96)00647-3

1,1'-iminodicarboxylic acid derivatives, which are similar to many natural substances can be synthesized in excellent yields and with high stereoselectivity by a one-pot reaction of α-amino acids, aldehydes, isocyanides and alcohols.