Chemoenzymatic synthesis of both enantiomers of cis-6-hydroxymethylpipecolic acid

DOI: 10.1016/0957-4166(96)00260-1

Source and publish data:

Tetrahedron Asymmetry p. 2161 - 2164 (1996)

Update date:2022-08-03

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Authors:

Chenevert, Robert

Morin, Marie-Pascale

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Article abstract of DOI:10.1016/0957-4166(96)00260-1

Both enantiomers of cis-6-hydroxymethylpipecolic acid, a piperidine-based non-proteinogenic amino acid, have been synthesized in high enantiopurity (ee ≤ 98%) via an enzymatic desymmetrization procedure.

Full text of DOI:10.1016/0957-4166(96)00260-1

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Product name:(-)-N-(benzyloxycarnonyl)-cis-2(R)-(acetoxymethyl)-6(S)-<(methoxymethoxy)methyl>piperidine

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