
Tetrahedron Letters p. 8985 - 8988 (1996)
Update date:2022-08-04
Topics:
Robl, Jeffrey A.
Sieber-McMaster, Ellen
Sulsky, Richard
Three diverse synthetic routes to C-7 dialkylated and spiro-alkylated azepinones are described. Compounds of this type may be used as conformationally restricted dipeptide surrogates. Additionally, the chiral synthesis of novel cyclopropanated lysine derivative 29 is demonstrated. Copyright (C) 1996 Elsevier Science Ltd.
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