Journal of the Chemical Society. Perkin transactions I p. 2371 - 2377 (1996)
Update date:2022-08-04
Topics:
Harris, Joanna M.
Watkins, William J.
Hawkins, Alastair R.
Coggins, John R.
Abell, Chris
Syntheses of 5-deoxydehydroquinic acid and 4,5-dideoxydehydroquinic acid from quinic acid are described. These substrate analogues were tested against the mechanistically-distinct type I and type II dehydroquinases. The C-4 hydroxy group of the substrate is shown to be important for imine formation on the type I enzyme but appears not to contribute significantly to specificity on the type II dehydroquinase.
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Doi:10.1039/dt9960004003
(1996)Doi:10.1021/ic960451d
(1996)Doi:10.1016/0957-4166(96)00372-2
(1996)Doi:10.1002/anie.201206362
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(1996)Doi:10.1246/cl.1974.701
(1974)
