Nucleosides, nucleotides and nucleic acids p. 1805 - 1820 (2000)
Update date:2022-08-02
Topics:
Gritsenko
Mikhailov
Efimtseva
Van Aerschot
Herdewijn
Gromova
Affinity labeling of methyltransferase MvaI by DNA duplexes containing oxidized 2′-O-β-D-ribofuranosylcytidine or 1-(β-D-galactopyranosyl)thymine residues was performed. Partial chemical hydrolysis of the covalently bound methylase in the conjugates with the dialdehyde-containing DNA allowed us to determine the amino acid region in the C terminus of methylase MvaI that interacts with DNA.
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