Difluorination of 2-substituted 1,1,1-tris(methylthio)ethanes by oxidative desulfurization-fluorination. A new route to partially fluorinated olefins

DOI: 10.1016/0040-4039(96)01788-1

Source and publish data:

Tetrahedron Letters p. 7983 - 7986 (1996)

Update date:2022-07-30

Topics:

Authors:

Furuta, Satoru

Hiyama, Tamejiro

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Article abstract of DOI:10.1016/0040-4039(96)01788-1

Oxidative desulfurization-fluorination of RCH₂C(SMe)₃ using n-Bu₄NH₂F₃ and 1,3-dibromo-5,5-dimethylhydantoin gave RCHBrCF₂SMe in good yields. The products were converted into difluorobromo olefins. Under similar conditions ArCH₂C(SMe)₃ afforded ArCBr₂CF₂SMe. The mechanism of the partial difluorination accompanied by bromination is discussed.

Full text of DOI:10.1016/0040-4039(96)01788-1

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