Solid phase ring-closing metathesis: Cyclization/cleavage approach towards a seven membered cycloolefin

Article abstract of DOI:10.1016/0040-4039(96)01881-3

The application of solid phase ring-closing metathesis (RCM) in a cyclization/cleavage strategy was demonstrated for the first time by the successful synthesis of the seven membered cycloolefin 4. Probably due to intermolecular metathetical dimerizations at the resin, 4 could not be obtained in higher yields than 54%.