New marine prostanoids, preclavulone lactones, from the Okinawan soft coral Clavularia viridis

DOI: 10.1016/S0040-4039(97)10211-8

Source and publish data:

Tetrahedron Letters p. 8319 - 8322 (1997)

Update date:2022-08-03

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Authors:

Iwashima, Makoto

Watanabe, Kinzo

Iguchi, Kazuo

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Article abstract of DOI:10.1016/S0040-4039(97)10211-8

Two new marine prostanoids, preclavulone lactones I (1) and II (2) were isolated from the Okinawan soft coral, Clavularia viridis. Their structures were determined based on spectroscopic analysis and chemical synthesis from (S)-malic acid. Preclavulone lactones with side chains having absolute configurations opposite to those of mammalian prostanoids could be recognized as key intermediates in biosynthesis of clavulones.

Full text of DOI:10.1016/S0040-4039(97)10211-8

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