
Tetrahedron Letters p. 8113 - 8116 (1996)
Update date:2022-08-03
Topics:
Sisko, Joseph
Mellinger, Mark
Sheldrake, Peter W.
Baine, Neil H.
Substituted tosylmethyl isocyanides (TosMICs) are useful reagents for which no general method of preparation is available. We describe here a high-yielding method for the synthesis of substituted tosylmethyl formamides, which are readily converted to the corresponding isocyanides.
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Doi:10.1039/CC9960002439
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(1969)