Tetrahedron Letters p. 1633 - 1636 (1997)
Update date:2022-08-03
Topics:
Martin, Ricardo
Pascual, Oscar
Romea, Pedro
Rovira, Roser
Urpi, Felix
Vilarrasa, Jaume
Amides derived from pyrrolidine and methyl (S)-lactate, methyl (S)-2-hydroxy-3-phenylpropanoate, or methyl (S)-2-hydroxy-3-methylbutanoate, after O-benzylation and O-silylation have been treated with EtLi or EtMgCl under suitable conditions, to give excellent overall yields of enantiopure ethyl ketones. The chelating ability of α-OBn amides (and even of α-O-TBS amides, which has been demonstrated by NMR to be better than that of N-OMe amides) accounts for the performance of the approach.
View MoreShanggao Ruiya Fine Chemicals Co., Ltd
Contact:+86-795-2592103
Address:Xingguang Nanlu,Shanggao County Industry Park
Jinan Trio PharmaTech Co., Ltd
Contact:86-531-88811783；+(0)13153010282
Address:2766 Yingxiu Road, Jinan High-Tech Zone, China
Jiangsu Willing Bio-Tech Co ltd
website:http://www.willingbio.com/
Contact:+86 18796908173
Address:No 18 Guoqiao Road
Contact:21-7631221 15884421033
Address:326 Science and technology,Shanghai,China
Shaanxi King Stone Enterprise Company Limited
Contact:86-29-88353805,13609285751
Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
Doi:10.1021/jo980320p
(1998)Doi:10.1016/j.bmcl.2006.04.043
(2006)Doi:10.1021/jo970121q
(1997)Doi:10.1021/ja00397a031
(1981)Doi:10.1016/S0040-4020(98)00474-8
(1998)Doi:10.1039/a606590b
(1997)
