Tetrahedron Letters p. 1633 - 1636 (1997)
Update date:2022-08-03
Topics:
Martin, Ricardo
Pascual, Oscar
Romea, Pedro
Rovira, Roser
Urpi, Felix
Vilarrasa, Jaume
Amides derived from pyrrolidine and methyl (S)-lactate, methyl (S)-2-hydroxy-3-phenylpropanoate, or methyl (S)-2-hydroxy-3-methylbutanoate, after O-benzylation and O-silylation have been treated with EtLi or EtMgCl under suitable conditions, to give excellent overall yields of enantiopure ethyl ketones. The chelating ability of α-OBn amides (and even of α-O-TBS amides, which has been demonstrated by NMR to be better than that of N-OMe amides) accounts for the performance of the approach.
View MoreZibo Linzi Darong Fine Chemical Co., Ltd(expird)
Contact:86-532-67773200; 15689126900
Address:Qidu town,Linzi district,Zibo city,Shandong province,China
Contact:86-607-68073220
Address:1 ave na road jiahua st
Wuxi Innopal International Trade CO.,LTD
Contact:+86-510-80711901-8003
Address:Room 402,Building 5,Longze Garden,No.17,South huanjiu Road,Yixing City, Jiangsu,China
Shanghai Dynamic Industrial Co.,Ltd.
website:http://www.shdynamic.com
Contact:86-021 3392 6680
Address:Room 805 Information Tower, No.1403 Minsheng Road, Pudong New Area, Shanghai 200135, P. R. China
Changsha Huajing Powdery Material Technological Co., Ltd.
Contact:86-731-88879686
Address:Building 2, West Garden, Main Campus of Central South University, Changsha, Hunan Province, China
Doi:10.1021/jo980320p
(1998)Doi:10.1016/j.bmcl.2006.04.043
(2006)Doi:10.1021/jo970121q
(1997)Doi:10.1021/ja00397a031
(1981)Doi:10.1016/S0040-4020(98)00474-8
(1998)Doi:10.1039/a606590b
(1997)
