Synthesis of (2S,1'S,2'S)-2-methyl-2-(carboxycyclopropyl)glycine and (S)-2-amino-2-methyl-4-phosphonobutyric acid from L-alanine

Article abstract of DOI:10.1016/S0957-4166(97)00031-1

The synthesis of two isotype-selective antagonists for metabotropic glutamate receptors, (2S,1'S,2'S)-2-methyl-2-(carboxycyclopropyl)glycine (S)-2-amino-2-methyl-4-phosphonobutyric acid from L-alanine is described.