Synthesis and reactions of a chemical model of the urocanase reaction

Article abstract of DOI:10.1002/chem.19970030312

Using a convergent synthetic strategy starting from nicotinic acid and imidazole, we have prepared the (E) and (Z) isomers of 1-benzyl-3-carbamoyl-5-[2-(ethoxycarbonylmethylene)-2(1-(p-tolylsulfamoyl)i midazol-4-yl)ethyl]pyridinium bromide (21) as models