Bioorganic and Medicinal Chemistry Letters p. 799 - 804 (1997)
Update date:2022-08-04
Topics:
Kassiou, Michael
Read, Roger W.
Shi, Xue-Qin
Syntheses of four novel amide analogues of the muscarinic M2 receptor antagonists, DIBA and BIBN 140, are described from a common intermediate. Pharmacological evaluation through in vitro assays reveals high muscarinic receptor affinity in each of the compounds, but variable subtype selectivity, primarily M2 but in one case M3.
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Doi:10.1055/s-1998-2018
(1998)Doi:10.1016/S0040-4039(97)00580-7
(1997)Doi:10.1016/j.bioorg.2018.05.006
(2018)Doi:10.1107/S0108270197002060
(1997)Doi:10.1002/bkcs.10446
(2015)Doi:10.1016/S0040-4020(97)00310-4
(1997)
