Novel asymmetric synthesis of penaresidin B as a potent actomyosin ATPase activator

Article abstract of DOI:10.1016/S0040-4039(97)00603-5

An efficient and novel synthetic process is described for the preparation of an azetidine ring with the contiguous stereogenic centers and the total synthesis of penaresidin B by featuring the elaboration ofthe functionalized homochiral lactam derived from D-glutamic acid.