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Sugar-Substituted 2-Azetidinone Cholesterol Absorption Inhibitors: Enhanced Potency by Modification of the Sugar

DOI: 10.1016/S0960-894X(98)00008-0

Source and publish data:

Bioorganic and medicinal chemistry letters p. 313 - 318 (1998)

Update date:2022-07-31

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Authors:

Vacarro, Wayne D.Vacarro, Wayne D.

Davis, Harry R.Davis, Harry R.

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Article abstract of DOI:10.1016/S0960-894X(98)00008-0

A glucuronide conjugate of the potent 2-azetidinone cholesterol absorbtion inhibitor Sch 58235 was synthesized to confirm the structure of a metabolite isolated from in vivo sources.A series of 2-azetidinone glycosides was prepared via Schmidt trichloroim

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Full text of DOI:10.1016/S0960-894X(98)00008-0

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Product name:Acetic acid (S)-1-(4-fluoro-phenyl)-3-{(3R,4S)-1-(4-fluoro-phenyl)-2-oxo-4-[4-((2S,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-azetidin-3-yl}-propyl ester

Cas No:190448-62-5

190448-62-5

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