Synthesis of monohydroxylated 2-azabicyclo[2.2.1]heptan-3-ones

DOI: 10.1016/S0960-894X(97)00217-5

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1299 - 1302 (1997)

Update date:2022-08-05

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Authors:

Palmer, Christopher F.

Webb, Ben

Broad, Susan

Casson, Sharon

McCague, Raymond

Willetts, Andrew J.

Roberts, Stanley M.

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Article abstract of DOI:10.1016/S0960-894X(97)00217-5

Oxymercuration/demercuration of 2-benzyl-2-azabicyclo[2.2.1]hept-5-en-3-one (1) and biohydroxylation of the corresponding saturated lactam (-)-(8) are compared as methods for the preparation of monohydroxylated 2-azabicyclo[2.2.1]heptan-3-ones.

Full text of DOI:10.1016/S0960-894X(97)00217-5

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