Novel and versatile synthesis of pyrrolidine type azasugars, DAB-1 and LAB-1, potent glucosidase inhibitors

DOI: 10.1016/S0040-4020(97)00445-6

Source and publish data:

Tetrahedron p. 7501 - 7508 (1997)

Update date:2022-07-29

Topics:

Authors:

Kim, Yong Jip

Kido, Masaru

Bando, Masahiko

Kitahara, Takeshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(97)00445-6

Synthesis or glucosidase inhibitors, DAB-1 (1) and LAB-1 (2) from diethyl tartrate is described. The procedure afforded an epimerizable mixture of diastereomeric intermediates 8 and ent. 8, and opened the door not only to the selective synthesis or DAB-1 and LAB-1 but for giving various related analogs.

Full text of DOI:10.1016/S0040-4020(97)00445-6

Products guided by the article

Product name:(2R,3R)-N-(4-methoxybenzyl)-2,3-dihydroxy-4-cyanopyrrolidine

Cas No:191723-92-9

R&D Labs maybe for 191723-92-9

Changzhou Sunsheng Chem Co., Ltd

Contact:+1-(989)-854-0648

Address:No. 28 Yinshan Rd., Xixiashu Industrial Park
zonk drug r&d limited

Contact:+86-20-32051076

Address:1105,Building A, International Business Incubator,Science City
Chongqing Werlchem Fine Chemical Co. Ltd

Contact:+86-23-67521957

Address:NO.15,Fortune Road,Yubei District,401121,Chongqing,China
Shandong Ailitong New Material Co.,Ltd

Contact:+86-536-3226266

Address:zhongjia village, putong town , qingzhou city,Shandong Province,China
Zha Yan

Contact:+86-13914766747

Address:Floors 21&22, Jin Cheng Tower, No. 216 Middle Longpan Road, Nanjing

Relevant to this article

An efficient access to β-ketosulfones: Via β-sulfonylvinylamines: Metal-organic framework catalysis for the direct C-S coupling of sodium sulfinates with oxime acetates

Doi:10.1039/c8ra02389a
(2018)
Doi:10.1016/S0040-4020(01)82872-6
(1969)
Studies on analgesics of aniline series. II. Preparation and properties of N-alkyl or N,N-dialkyl 3-(N'-acyl-or N'-benzyl-substituted anilino)propionamide series and N-alkyl or N,N-dialkyl 3-(substituted anilino)propylamine series.

Doi:10.1248/cpb.13.205
(1965)
Isomerization of Trimethyl α-Keto Trithioorthocarboxylates into α,α-Bis(methylthio) Thiolcarboxylates. A New Rearrangement of Synthetic Interest

Doi:10.1021/jo970683+
(1997)
Studies on pyrimidine derivatives. X.

Doi:10.1248/cpb.16.750
(1968)
Stereoselective [2,3]-Wittig and tandem [2,3]-Wittig-anionic oxy-Cope rearrangements of bis-allylic ethers: Effect of substituents

Doi:10.1016/S0040-4039(97)01473-1
(1997)

Article Doi